Blood Typing in Cats and Dogs

✳️Purpose of Blood Testing

• Decrease Immunological Transfusion Reactions

• Decrease Risk of Neonatal Isoerythrolysis (Breeding Cats)

🧪Methods of Testing

• Laboratory Methods

  1. Slide or Tube Typing (Known Alloantibodies)

  2. Reference Laboratories (Commercial Antibodies)

• Point-of-Care Options

A. Card-Based Typing

• Lyophilized Monoclonal Antibody

• Agglutination Indicates Positive

• Available for: DEA 1, 4, 5 (Dogs), Dal Antigen (Dogs), AB Typing (Cats)

B. Immunochromatographic Membrane Test Kits

• Membrane Embedded with Monoclonal Antibody

• Used for: DEA 1 Detection (Dogs), Weak DEA 1 Expression (Dogs), AB Detection (Cats)
  
  

🐕Dog Blood Types Tested

• DEA 1

• DEA 4

• DEA 5

• Dal Antigen

🐈Cat Blood Types Tested

• AB System
  
  

Sources/Authorship

1. Shauna Blois, DVM, DVSc, DACVIM-SAIM

2. University of Guelph, Ontario Veterinary College

3. Reviewed/Revised: November 2024

4. Merck Veterinary Manual (2025)

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